Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6- difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non- nucleoside inhibitors of HIV-1 reverse transcriptase

Mai, A., Sbardella, G., Artico, M., Ragno, R., Massa, S., Novellino, E., Greco, G., Lavecchia, A., Musiu, C., La Colla, M., Murgioni, C., La Colla, P., and Loddo, R. . Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6- difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non- nucleoside inhibitors of HIV-1 reverse transcriptase. Journal of Medicinal Chemistry 44, 2544-54. 2001

Establish of Alchemical Dynamics a Sapienza Start-Up

In may 2016 Prof Rino Ragno together with Dr Alexandros Patsilinakos and Dr Roberto Manganaro founded a new company named Alchemical Dynamics srl. As Rino ragno is a Sapienza University employ the company started with the permission of Department of Drug Chemistry and Technology, Sapienza University Senate and Sapienza University Board of Directors (BOD – consiglio di amministrazione – CDA).